The episode opens with Sam and Dean tailing a figure in black, and it is not a chase that bodes well for Dean. The figure is hovering over a body and glowing red, and so Dean charges in, as he always does. With a flash, he is gone and we are taken back to two days ago.

The brothers get a call from Sheriff Mills about a mysterious death of a grad student. When he was found, the youth resembled a mummy. This is clearly something for the Winchester boys so they set out to survey the town and set up camp in an abandoned house. Their first witness describes the opening scene of the episode, and so the brothers begin researching strange deaths in the area. Canton is known for their withered corpses, and the mummies appear in groups of three. Two have died in this area already, so the brothers wait for the next victim.

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